PODCAST SERIES: When Methodology Meets Technology: Exploring how intelligent trial design and digital agility reshape clinical trials
Group sequential designs can help clinical trial teams make earlier decisions on efficacy or futility—but their success depends on having the right data available at the right time.
Episode 2: Turning Data Into Decisions: Real-Time Reporting Meets Group-Sequential Designs
In this episode, IDDI and Marvin EDC experts take a closer look at the methodology and technology behind group sequential designs. From interim analysis timing and spending functions to continuous data checks and real-time reporting, they explore what it takes to support reliable decisions during an ongoing trial. Discover why aligning statistical planning, EDC configuration and data-cut workflows from the start is essential for a smooth and efficient interim analysis.
Speakers:
- Leandro Garcia Barrado, Principal Statistical Scientist, IDDI
- Tom Brain, Product Specialist, Marvin EDC by AB Cube
Key Learnings:
- Understand how group sequential designs work: Using interim analyses to support earlier efficacy or futility decisions
- Explore the role of timing and spending functions: Balancing interim decisions with statistical rigor
- See why real-time data readiness matters: Ensuring reliable data are ready for interim analysis
- Connect trial design with EDC implementation: Aligning biostatistics, EDC and data workflows from the start
Watch episode 1: From Protocol to Platform: Flexible Randomization and Seamless Design in Practice
Watch episode 3: From Data to Delivery: EDC’s Role in Accelerated Approvals and Trustworthy Evidence
Continue the conversation at our upcoming webinar:
Project Optimus Meets EDC: Operationalizing Optimal Dose Trials from Design to Data
Thursday 15 October | 4pm CET / 10am ET
About the podcast series:
When Methodology Meets Technology explores how intelligent trial design and digital agility can work together to address the growing complexity of clinical research. Across three episodes, experts from IDDI and Marvin EDC discuss how statistical innovation, connected data and flexible technology can help translate advanced trial designs into clinical practice.
