Discovering New Prognostic Biomarkers For Breast Cancer

New prognostic biomarkers for breast cancer: A range of biological markers were analyzed by polymerase chain reaction and immunohistochemistry in tissue microarrays from patients treated in several past and ongoing clinical trials for breast cancer. The obtained marker measurements were combined with the clinical data and analyzed using survival analysis methodology, including some advanced modeling techniques, to investigate whether any of the markers had prognostic value. The investigation was successful for at least one of the potential markers analyzed. The project is ongoing to validate further biologically interesting candidate biomarkers.